Ligand · HMH
HMH · 4-amino-5-hydroxymethyl-2-methylpyrimidine
HMH, 4-amino-5-hydroxymethyl-2-methylpyrimidine (C6 H9 N3 O, 139.2 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…
- Component
- HMH
- Formula
- C6 H9 N3 O
- Class
- ligand
- Structures
- 16
- PDB entries
- 8
Binding sites
HMH in 16 structures; the first of them:
- 1JXI · 4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium… · HMH A2001 · binds GLY11, THR12, ALA18, GLY19, VAL42, GLU44, MET80, VAL107 and 4 more
- 1TO9 · Crystal structure of THI-4 protein from Bacillus subtilis · HMH A301 · binds TYR40, ASP44, TYR47, LEU48, ALA81, LEU85, CYS135, TYR139 and 3 more
- 1YAK · Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine · HMH A301 · binds TYR40, ASP44, TYR47, LEU48, TYR112, CYS135, TYR139, TYR163 and 3 more
- 2F2G · X-Ray Structure of Gene Product From Arabidopsis Thaliana AT3G16990 · HMH A1300 · binds ASP47, PHE50, VAL51, TYR115, ILE139, GLU140, VAL142, TYR143 and 3 more
- 2GM8 · TenA Homolog/Thi-4 Thiaminase complexed with product… · HMH A301 · binds ASP43, TYR46, LEU47, GLU81, TYR85, TYR111, CYS134, PHE135 and 5 more
- 2Q4X · Ensemble refinement of the protein crystal structure of gene product from Arabidopsis… · HMH A1300 · binds ASP47, PHE50, VAL51, GLU88, TYR115, ILE139, GLU140, VAL142 and 4 more
- 3EPM · Crystal structure of Caulobacter crescentus ThiC · HMH A1001 · binds LEU250, TYR277, HIS313, VAL332, SER333, ARG334, GLY335, ARG377
- 7R8Y · Ancestral protein AncThEn of Phosphomethylpyrimidine kinases family · HMH A301 · binds GLY9, SER10, ASP11, ALA16, GLY17, GLN42, MET78, VAL107 and 4 more
- 1JXI · 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from salmonella typhimurium… · HMH A2001 · binds GLY11, THR12, ALA18, GLY19, VAL42, GLU44, MET80, VAL107 and 4 more
- 1TO9 · Crystal structure of thi-4 protein from bacillus subtilis · HMH A301 · binds TYR40, ASP44, TYR47, LEU48, ALA81, LEU85, CYS135, TYR139 and 3 more
- 1YAK · Complex of bacillus subtilis tena with 4-amino-2-methyl-5- hydroxymethylpyrimidine · HMH A301 · binds TYR40, ASP44, TYR47, LEU48, TYR112, CYS135, TYR139, TYR163 and 3 more
- 2F2G · X-ray structure of gene product from arabidopsis thaliana AT3G16990 · HMH A1300 · binds ASP47, PHE50, VAL51, TYR115, ILE139, GLU140, VAL142, TYR143 and 3 more
- 2GM8 · Tena HOMOLOG/THI-4 thiaminase complexed with product 4-amino-5… · HMH A301 · binds ASP43, TYR46, LEU47, GLU81, TYR85, TYR111, CYS134, PHE135 and 5 more
- 2Q4X · Ensemble refinement of the protein crystal structure of gene product from arabidopsis… · HMH A1300 · binds ASP47, PHE50, VAL51, GLU88, TYR115, ILE139, GLU140, VAL142 and 4 more
- 3EPM · Crystal structure of caulobacter crescentus thic · HMH A1001 · binds LEU250, TYR277, HIS313, VAL332, SER333, ARG334, GLY335, ARG377
- 7R8Y · Ancestral protein ancthen of phosphomethylpyrimidine kinases family · HMH A301 · binds GLY9, SER10, ASP11, ALA16, GLY17, GLN42, MET78, VAL107 and 4 more
Residues it binds most
TYR 30, PHE 28, GLU 32, ASP 30, CYS 26, LEU 24, VAL 16, GLY 8, ALA 8, ILE 8 (residue and the binding sites it lines).
Found with
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