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Ligand · HM5

HM5 · 3-[(2,2-dimethylpropanoyl)amino]-N-1,3-thiazol-2-ylpyridine-2-carboxamide

HM5, 3-[(2,2-dimethylpropanoyl)amino]-N-1,3-thiazol-2-ylpyridine-2-carboxamide (C14 H16 N4 O2 S, 304.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
HM5
Formula
C14 H16 N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

HM5 in 2 structures; the first of them:

  • 2NQ7 · Crystal structure of type 1 human methionine aminopeptidase in complex with… · HM5 A410 · binds PRO192, TYR195, TYR196, PHE198, CYS203, HIS212, CYS301, PHE309 and 2 more
  • 2NQ7 · Crystal structure of type 1 human methionine aminopeptidase in complex with… · HM5 A410 · binds PRO192, TYR195, TYR196, PHE198, CYS203, HIS212, CYS301, PHE309 and 2 more

Residues it binds most

CYS 2, HIS 2, PHE 2, TYR 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • CO · Cobalt (II) ion
  • K · Potassium ion
  • GOL · Glycerol

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