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Ligand · HL0

HL0 · N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide

HL0, N-[(3S)-2-oxotetrahydrofuran-3-yl]decanamide (C14 H25 N O3, 255.3 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
HL0
Formula
C14 H25 N O3
Class
ligand
Structures
7
PDB entries
5

Binding sites

HL0 in 7 structures; the first of them:

  • 3QP4 · Crystal structure of CviR ligand-binding domain bound to C10-HSL · HL0 A1 · binds LEU57, LEU72, VAL75, TYR80, TRP84, LEU85, TYR88, MET89 and 11 more
  • 3QP8 · Crystal structure of CviR (Chromobacterium violaceum 12472) ligand-binding domain bound… · HL0 A1 · binds ILE57, VAL59, MET72, VAL75, TYR80, TRP84, LEU85, TYR88 and 14 more
  • 9ISS · Crystal Structure of Cytochrome P450BM3 III-10C1 Mutant Heme Domain with… · HL0 A502 · binds LEU20, PRO25, VAL26, LEU29, TRP47, LEU49, TYR51, SER72 and 8 more
  • 9IST · Crystal Structure of Cytochrome P450BM3 VI-18A12 Mutant Heme Domain with… · HL0 A502 · binds LEU20, VAL25, VAL26, LEU29, TRP47, LEU49, TYR51, SER72 and 9 more
  • 9ISU · Crystal Structure of Cytochrome P450BM3 V-19A14 Mutant Heme Domain with… · HL0 A502 · binds LEU20, VAL25, VAL26, LEU29, TRP47, LEU49, TYR51, SER72 and 10 more
  • 3QP4 · Crystal structure of cvir ligand-binding domain bound to C10-hsl · HL0 A1 · binds LEU57, LEU72, VAL75, TYR80, TRP84, LEU85, TYR88, MET89 and 11 more
  • 3QP8 · Crystal structure of cvir (chromobacterium violaceum 12472) ligand- binding domain bound… · HL0 A1 · binds ILE57, VAL59, MET72, VAL75, TYR80, TRP84, LEU85, TYR88 and 14 more

Residues it binds most

LEU 16, MET 16, VAL 16, ILE 10, PHE 16, TRP 16, TYR 16, ALA 16, SER 16, PRO 8 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • DMS · Dimethyl sulfoxide
  • GOL · Glycerol

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