GL1X · GenesisL1 explorer

Ligand · HK8

HK8 · (3-chloro-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl)acetic acid

HK8, (3-chloro-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-8-yl)acetic acid (C15 H11 Cl N2 O3, 302.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
HK8
Formula
C15 H11 Cl N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

HK8 in 2 structures; the first of them:

  • 4FSZ · Crystal Structure of the CHK1 · HK8 A301 · binds GLN13, LEU15, GLY16, VAL23, ALA36, GLU85, TYR86, CYS87 and 4 more
  • 4FSZ · Crystal structure of the CHK1 · HK8 A301 · binds GLN13, LEU15, GLY16, VAL23, ALA36, GLU85, TYR86, CYS87 and 4 more

Residues it binds most

GLU 2, GLY 2, LEU 2, ALA 2, CYS 2, GLN 2, SER 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • IPA · Isopropyl alcohol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.