Ligand · HIZ
HIZ · 1-{4-[(1S)-1-amino-2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-(3-chloro-4-fluorophenyl)urea
HIZ, 1-{4-[(1S)-1-amino-2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-(3-chloro-4-fluorophenyl)urea (C19 H18 Cl F N4 O2 S, 420.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…
- Component
- HIZ
- Formula
- C19 H18 Cl F N4 O2 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
HIZ in 2 structures; the first of them:
- 3IW8 · Structure of Inactive Human p38 MAP Kinase in Complex with a Thiazole-Urea · HIZ A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, VAL83, ILE84 and 11 more
- 3IW8 · Structure of inactive human P38 MAP kinase in complex with a thiazole- urea · HIZ A361 · binds VAL38, ALA51, LYS53, GLU71, LEU74, LEU75, VAL83, ILE84 and 11 more
Residues it binds most
LEU 2, ILE 2, VAL 2, ALA 2, ASP 2, GLU 2, HIS 2, LYS 2, PHE 2, THR 2 (residue and the binding sites it lines).
Found with
- BOG · octyl beta-D-glucopyranoside
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