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Ligand · HIG

HIG · 2-ethyl-5,7-dimethyl-3-{(1S)-5-[2-(1H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl}-3H-imidazo[4,5-b]pyridine

HIG, 2-ethyl-5,7-dimethyl-3-{(1S)-5-[2-(1H-tetrazol-5-yl)phenyl]-2,3-dihydro-1H-inden-1-yl}-3H-imidazo[4,5-b]pyridine (C26 H25 N7, 435.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
HIG
Formula
C26 H25 N7
Class
ligand
Structures
2
PDB entries
1

Binding sites

HIG in 2 structures; the first of them:

  • 3R8A · X-ray crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a… · HIG A1 · binds ILE281, GLY284, CYS285, ARG288, SER289, ALA292, ILE326, TYR327 and 11 more
  • 3R8A · X-ray crystal structure of the nuclear hormone receptor ppar-gamma in a complex with a… · HIG A1 · binds ILE281, GLY284, CYS285, ARG288, SER289, ALA292, ILE326, TYR327 and 11 more

Residues it binds most

LEU 4, ILE 4, MET 4, SER 4, ALA 4, ARG 4, CYS 4, GLY 4, TYR 4, VAL 4 (residue and the binding sites it lines).

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