Ligand · HI0
HI0 · (R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide
HI0, (R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide (C43 H45 Cl N8 O4 S2, 837.5 g/mol), in the MolNFT structures on GenesisL1: bound…
- Component
- HI0
- Formula
- C43 H45 Cl N8 O4 S2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
HI0 in 2 structures; the first of them:
- 3QKD · Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor · HI0 A218 · binds ALA93, GLU96, PHE97, ARG100, TYR101, ALA104, PHE105, LEU108 and 16 more
- 3QKD · Crystal structure of BCL-xl in complex with a quinazoline sulfonamide inhibitor · HI0 A218 · binds ALA93, GLU96, PHE97, ARG100, TYR101, ALA104, PHE105, LEU108 and 16 more
Residues it binds most
PHE 4, ALA 4, ARG 4, GLU 4, LEU 4, TYR 4, VAL 4, ASN 4, GLY 4, SER 4 (residue and the binding sites it lines).
Found with
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