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Ligand · HFN

HFN · 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one

HFN, 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one (C21 H18 F3 N3 O3, 417.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
HFN
Formula
C21 H18 F3 N3 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

HFN in 2 structures; the first of them:

  • 4PF3 · Mineralocorticoid receptor ligand-binding domain with compuond 37a · HFN A1001 · binds LEU766, LEU769, ASN770, LEU772, ALA773, GLN776, TRP806, MET807 and 17 more
  • 4PF3 · Mineralocorticoid receptor ligand-binding domain with compuond 37A · HFN A1001 · binds LEU766, LEU769, ASN770, LEU772, ALA773, GLN776, TRP806, MET807 and 17 more

Residues it binds most

LEU 2, MET 2, PHE 2, CYS 2, ALA 2, ARG 2, ASN 2, GLN 2, SER 2, THR 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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