Ligand · HD2
HD2 · 4-cyclopentyl-N-[(1S,3R)-5-oxidanyl-2-adamantyl]-2-[[(3S)-oxolan-3-yl]amino]pyrimidine-5-carboxamide
HD2, 4-cyclopentyl-N-[(1S,3R)-5-oxidanyl-2-adamantyl]-2-[[(3S)-oxolan-3-yl]amino]pyrimidine-5-carboxamide (C24 H34 N4 O3, 426.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- HD2
- Formula
- C24 H34 N4 O3
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
HD2 in 4 structures; the first of them:
- 4BB5 · Free-Wilson and Structural Approaches to Co-optimising Human and Rodent Isoform Potency… · HD2 A1291 · binds ILE121, THR124, LEU126, SER170, LEU171, ALA172, TYR177, PRO178 and 14 more
- 5ALU · ligand complex structure of soluble epoxide hydrolase · HD2 A1548 · binds ASP11, VAL19, PHE20, PHE41, GLN42, GLY45, THR50, THR51 and 9 more
- 4BB5 · Free-wilson and structural approaches to co-optimising human and rodent isoform potency… · HD2 A1291 · binds ILE121, THR124, LEU126, SER170, LEU171, ALA172, TYR177, PRO178 and 14 more
- 5ALU · Ligand complex structure of soluble epoxide hydrolase · HD2 A1548 · binds ASP11, VAL19, PHE20, PHE41, GLN42, GLY45, THR50, THR51 and 9 more
Residues it binds most
LEU 10, TYR 10, VAL 12, ALA 8, THR 12, MET 14, ILE 14, PRO 14, SER 10, PHE 6 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.