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Ligand · HAM

HAM · Histidyl-adenosine monophosphate

HAM, Histidyl-adenosine monophosphate (C16 H21 N8 O8 P, 484.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
HAM
Formula
C16 H21 N8 O8 P
Class
ligand
Structures
6
PDB entries
3

Binding sites

HAM in 6 structures; the first of them:

  • 1ADY · Histidyl-tRNA synthetase in complex with histidyl-adenylate · HAM A423 · binds GLU81, GLY82, THR83, ARG112, GLU114, GLY119, ARG120, TYR121 and 22 more
  • 1KMM · Histidyl-tRNA synthetase complexed with histidyl-adenylate · HAM A450 · binds GLU83, THR85, TYR107, ARG113, GLU115, GLY120, ARG121, TYR122 and 21 more
  • 3HRK · Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidyl-adenylate complex) · HAM A1 · binds GLU126, THR128, ARG156, GLU158, GLY163, ARG164, ARG165, HIS168 and 19 more
  • 1ADY · Histidyl-tRNA synthetase in complex with histidyl-adenylate · HAM A423 · binds GLU81, GLY82, THR83, ARG112, GLU114, GLY119, ARG120, TYR121 and 22 more
  • 1KMM · Histidyl-tRNA synthetase complexed with histidyl-adenylate · HAM A450 · binds GLU83, THR85, TYR107, ARG113, GLU115, GLY120, ARG121, TYR122 and 21 more
  • 3HRK · Histidyl-tRNA synthetase from trypanosoma cruzi (histidyl-adenylate complex) · HAM A1 · binds GLU126, THR128, ARG156, GLU158, GLY163, ARG164, ARG165, HIS168 and 19 more

Residues it binds most

GLY 20, TYR 20, ARG 20, GLU 20, PHE 20, ALA 20, LEU 20, THR 20, GLN 20, CYS 12 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion

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