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Ligand · HA5

HA5 · (5R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid

HA5, (5R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid (C7 H8 N2 O4, 184.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
HA5
Formula
C7 H8 N2 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

HA5 in 2 structures; the first of them:

  • 3PD9 · X-ray structure of the ligand-binding core of GluA2 in complex with (R)-5-HPCA at 2.1 A… · HA5 A260 · binds TYR58, PRO86, LEU87, THR88, ARG93, LEU135, GLY138, SER139 and 5 more
  • 3PD9 · X-ray structure of the ligand-binding core of GLUA2 in complex with (R)-5-hpca at 2.1 a… · HA5 A260 · binds TYR58, PRO86, LEU87, THR88, ARG93, LEU135, GLY138, SER139 and 5 more

Residues it binds most

LEU 4, THR 4, TYR 4, ARG 4, GLU 4, GLY 4, MET 4, PRO 4, SER 4 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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