Ligand · H8I

H8I · [2-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone

H8I, [2-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone (C21 H16 Cl2 N2 O2, 399.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component: H8I
Formula: C21 H16 Cl2 N2 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

H8I in 2 structures; the first of them:

7XTQ · Cryo-EM structure of the R399-bound GPBAR-Gs complex · H8I R401 · binds LEU71, LEU74, TRP75, TYR89, ASN93, PHE96, SER157, PHE161 and 10 more
7XTQ · Cryo-EM structure of the R399-bound gpbar-gs complex · H8I R401 · binds LEU71, LEU74, TRP75, ASN93, PHE96, PHE161, LEU166, GLU169 and 6 more

Residues it binds most

LEU 2, SER 2, TYR 2, PHE 2, ASN 2, GLU 2, TRP 2, THR 1 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.