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Ligand · H4R

H4R · 4-[(1~{R},5~{S})-6-[2-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]ethynyl]-3-azabicyclo[3.1.0]hexan-3-yl]butanoic acid

H4R, 4-[(1~{R},5~{S})-6-[2-[4-[3-[[2-[(1~{S})-1-oxidanylethyl]imidazol-1-yl]methyl]-1,2-oxazol-5-yl]phenyl]ethynyl]-3-azabicyclo[3.1.0]hexan-3-yl]butanoic acid (C26 H28 N4 O4, 460.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
H4R
Formula
C26 H28 N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

H4R in 2 structures; the first of them:

  • 7DEN · Crystal structure of P.aeruginosa LpxC in complex with inhibitor · H4R A302 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 10 more
  • 7DEN · Crystal structure of P.AERUGINOSA lpxc in complex with inhibitor · H4R A302 · binds LEU18, HIS19, MET62, GLU77, HIS78, THR190, PHE191, GLY192 and 10 more

Residues it binds most

HIS 2, ALA 2, GLY 2, MET 2, ASP 2, GLU 2, ILE 2, LEU 2, PHE 2, SER 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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