GL1X · GenesisL1 explorer

Ligand · H41

H41 · N-[1-(N'-cyano-N-[3-(difluoromethoxy)phenyl]carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxyacetamide

H41, N-[1-(N'-cyano-N-[3-(difluoromethoxy)phenyl]carbamimidoyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxyacetamide (C22 H20 Cl2 F2 N6 O3, 525.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
H41
Formula
C22 H20 Cl2 F2 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

H41 in 2 structures; the first of them:

  • 5ARG · SMYD2 in complex with SGC probe BAY-598 · H41 A1432 · binds GLU104, THR105, LEU108, VAL179, ASN180, CYS181, ASN182, GLY183 and 13 more
  • 5ARG · SMYD2 in complex with sgc probe bay-598 · H41 A1432 · binds GLU104, THR105, LEU108, VAL179, ASN180, CYS181, ASN182, GLY183 and 13 more

Residues it binds most

THR 2, TYR 2, ASN 2, GLU 2, SER 2, VAL 2, ALA 2, CYS 2, GLY 2, ILE 2 (residue and the binding sites it lines).

Found with

  • SAM · S-adenosylmethionine
  • ZN · Zinc ion
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.