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Ligand · GZM

GZM · 4-[(3',5'-dichloro[1,1'-biphenyl]-4-yl)methyl]-N-ethyl-1-(methoxyacetyl)piperidine-4-carboxamide

GZM, 4-[(3',5'-dichloro[1,1'-biphenyl]-4-yl)methyl]-N-ethyl-1-(methoxyacetyl)piperidine-4-carboxamide (C24 H28 Cl2 N2 O3, 463.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
GZM
Formula
C24 H28 Cl2 N2 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

GZM in 2 structures; the first of them:

  • 7M2K · CDC34A-Ubiquitin-2ab inhibitor complex · GZM A201 · binds PHE28, ILE45, PHE46, GLY47, PRO48, ASN50, THR51, TYR52 and 9 more
  • 7M2K · CDC34A-ubiquitin-2AB inhibitor complex · GZM A201 · binds PHE46, PRO48, ASN50, THR51, TYR52, TYR53, PHE58, ILE128 and 6 more

Residues it binds most

TYR 8, PHE 8, ASN 8, ILE 8, GLY 8, THR 8, LEU 8, PRO 8, TRP 7, LYS 5 (residue and the binding sites it lines).

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