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Ligand · GZ3

GZ3 · (E)-2-methyl-3-phosphonoacrylate

GZ3, (E)-2-methyl-3-phosphonoacrylate (C4 H7 O5 P, 166.1 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
GZ3
Formula
C4 H7 O5 P
Class
ligand
Structures
3
PDB entries
2

Binding sites

GZ3 in 3 structures; the first of them:

  • 4UMA · Structural analysis of substrate-mimicking inhibitors in complex with Neisseria… · GZ3 A1351 · binds CYS63, ARG94, TYR96, LYS99, PRO100, GLU145, GLY165, ALA166 and 7 more
  • 8F6M · Complex of Rabbit muscle pyruvate kinase with ADP and the phosphonate analogue of PEP… · GZ3 E601 · binds ARG72, ASP112, LYS269, GLU271, MET290, ALA292, ARG293, GLY294 and 3 more
  • 4UMA · Structural analysis of substrate-mimicking inhibitors in complex with neisseria… · GZ3 A1351 · binds CYS63, ARG94, TYR96, LYS99, PRO100, GLU145, GLY165, ALA166 and 7 more

Residues it binds most

ARG 12, ASP 12, GLU 12, LYS 12, ALA 12, GLY 12, CYS 8, HIS 8, PRO 8, TYR 8 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • ADP · Adenosine-5'-diphosphate
  • ALA · Alanine
  • K · Potassium ion
  • GOL · Glycerol
  • SIN · Succinic acid

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