Ligand · GVZ
GVZ · (2~{S})-~{N}-[(2~{S},3~{R})-1-[(1~{S},4~{A}~{S}, 8~{A}~{R})-1,2,3,4,4~{A},5,6,7,8,8~{A}-decahydronaphthalen-1-yl]-4-methyl-3,4-bis(oxidanyl) pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide
GVZ, (2~{S})-~{N}-[(2~{S},3~{R})-1-[(1~{S},4~{A}~{S}, 8~{A}~{R})-1,2,3,4,4~{A},5,6,7,8,8~{A}-decahydronaphthalen-1-yl]-4-methyl-3,4-bis(oxidanyl) pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)…
- Component
- GVZ
- Formula
- C35 H56 N4 O7
- Class
- ligand
- Structures
- 1
- PDB entries
- 1
Binding sites
GVZ in 1 structure; the first of them:
- 6HVY · Yeast 20S proteasome in complex with 5 (7- and 6-membered ring) · GVZ H301 · binds THR1, ARG19, SER20, THR21, GLN22, CYS31, ALA32, LYS33 and 12 more
Residues it binds most
THR 2, ALA 2, GLY 2, SER 2, ARG 2, ASP 2, CYS 2, GLN 2, GLU 2, HIS 2 (residue and the binding sites it lines).
Found with
- GW2 · (2~{S})-~{N}-[(2~{S},3~{S},4~{R})-1-[(1~{S},4~{A}~{S}, 8~{A}~{R})-1,2,3,4,4~{A},5,6,7,8,8~{A}-decahydronaphthalen-1-yl]-4-methyl-3,5-bis(oxidanyl) pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino) propanoyl]amino]propanamide
- MG · Magnesium ion
- CL · Chloride ion
- MES · 2-(N-morpholino)-ethanesulfonic acid
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