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Ligand · GPA

GPA · 2-amino-3-guanidino-propionic acid

GPA, 2-amino-3-guanidino-propionic acid (C4 H10 N4 O2, 146.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
GPA
Formula
C4 H10 N4 O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

GPA in 4 structures; the first of them:

  • 4FCI · Crystal Structure of the Mn2+2-Human Arginase I-AGPA Complex · GPA A403 · binds HIS126, ASP128, ASN130, SER137, ASN139, HIS141, GLY142, ASP183 and 2 more
  • 4FCK · Crystal Structure of the Co2+2-Human Arginase I-AGPA Complex · GPA A401 · binds HIS126, ASP128, ASN130, THR135, SER137, ASN139, HIS141, GLY142 and 3 more
  • 4FCI · Crystal structure of the MN2+2-human arginase I-agpa complex · GPA A403 · binds HIS126, ASP128, ASN130, SER137, ASN139, HIS141, GLY142, ASP183 and 2 more
  • 4FCK · Crystal structure of the CO2+2-human arginase I-agpa complex · GPA A401 · binds HIS126, ASP128, ASN130, THR135, SER137, ASN139, HIS141, GLY142 and 3 more

Residues it binds most

ASN 6, ASP 6, HIS 6, THR 6, GLU 6, GLY 6, SER 6 (residue and the binding sites it lines).

Found with

  • CO · Cobalt (II) ion
  • MN · Manganese (II) ion

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