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Ligand · GN4

GN4 · 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose

GN4, 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose (C8 H16 N O9 P, 301.2 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
GN4
Formula
C8 H16 N O9 P
Class
sugar
Structures
6
PDB entries
3

Binding sites

GN4 in 6 structures; the first of them:

  • 5DQ9 · Structure of S55-3 Fab in complex with Lipid A · GN4 E2 · binds GLY33, ILE51, SER52, ASN52A, HIS95, LYS96, GLY100A, THR100B and 2 more
  • 5DQD · Structure of S55-5 Fab in complex with lipid A carbohydrate backbone · GN4 A2 · binds ARG96, GLY33, LEU50, ILE51, SER52, ARG52A, TYR56, HIS95 and 3 more
  • 6DFE · The structure of a ternary complex of E. coli WaaC · GN4 C2 · binds ARG60, ARG63, LEU96, LYS98, GLU121
  • 5DQ9 · Structure of S55-3 Fab in complex with lipid a · GN4 E2 · binds GLY33, ILE51, SER52, ASN52A, HIS95, LYS96, GLY100A, THR100B and 2 more
  • 5DQD · Structure of S55-5 Fab in complex with lipid a carbohydrate backbone · GN4 A2 · binds ARG96, GLY33, LEU50, ILE51, SER52, ARG52A, TYR56, HIS95 and 3 more
  • 6DFE · The structure of a ternary complex of E. COLI waac · GN4 C2 · binds ARG60, ARG63, LYS98, GLU121

Residues it binds most

ARG 12, GLY 8, ASN 8, HIS 8, ILE 8, LEU 8, SER 8, THR 8, LYS 6, GLU 4 (residue and the binding sites it lines).

Found with

  • GN1 · 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose
  • CL · Chloride ion
  • GA7 · [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R)-1-{(2S,3S, 4R,5S,6R)-6-[(1S)-1,2-dihydroxyethyl]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}propan-2-yl hydrogen (R)-phosphate (non-preferred name)
  • KDO · 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid

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