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Ligand · GK5

GK5 · N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide

GK5, N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide (C22 H24 N2 O2, 348.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
GK5
Formula
C22 H24 N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

GK5 in 2 structures; the first of them:

  • 3D7Z · Crystal Structure of P38 Kinase in Complex with a biphenyl amide inhibitor · GK5 A401 · binds TYR35, VAL38, ALA51, VAL52, LYS53, GLU71, LEU74, LEU75 and 14 more
  • 3D7Z · Crystal structure of P38 kinase in complex with a biphenyl amide inhibitor · GK5 A401 · binds TYR35, VAL38, ALA51, VAL52, LYS53, GLU71, LEU74, LEU75 and 14 more

Residues it binds most

LEU 2, ALA 2, ASP 2, VAL 2, GLU 2, GLY 2, HIS 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol

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