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Ligand · GHF

GHF · N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide

GHF, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide (C26 H25 F N4 O4, 476.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
GHF
Formula
C26 H25 F N4 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

GHF in 2 structures; the first of them:

  • 7XNE · Crystal structure of CBP bromodomain liganded with Y08284 · GHF A1201 · binds LEU1109, PRO1110, PHE1111, ARG1112, GLN1113, VAL1115, LEU1120, ILE1122 and 12 more
  • 7XNE · Crystal structure of cbp bromodomain liganded with Y08284 · GHF A1201 · binds LEU1109, PRO1110, GLN1113, VAL1115, LEU1120, ILE1122, ASN1168, ARG1173 and 6 more

Residues it binds most

LEU 4, VAL 4, GLN 4, ARG 3, ASN 4, ILE 4, PHE 2, PRO 4, TYR 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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