Ligand · GDM
GDM · Geldanamycin
GDM, Geldanamycin (C29 H40 N2 O9, 560.6 g/mol), in the MolNFT structures on GenesisL1: bound in 20 records (10 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- GDM
- Formula
- C29 H40 N2 O9
- Class
- ligand
- Structures
- 20
- PDB entries
- 10
Binding sites
GDM in 20 structures; the first of them:
- 1A4H · Structure of the N-terminal domain of the yeast HSP90 chaperone in complex with… · GDM A300 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 1YET · Geldanamycin bound to the HSP90 geldanamycin-binding domain · GDM A275 · binds ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96, MET98 and 11 more
- 2ESA · GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA · GDM A401 · binds ASN107, ALA108, ASP110, ALA111, LYS114, ASP149, VAL152, MET154 and 10 more
- 2EXL · GRP94 N-terminal Domain bound to geldanamycin · GDM A301 · binds ASN107, ALA108, ASP110, ALA111, LYS114, ASP149, VAL152, MET154 and 10 more
- 2WEQ · Yeast Hsp90 N-terminal domain LI-IV mutant with Geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 2YGA · E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 11 more
- 2YGE · E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, ARG44, ASP79, ILE82, MET84 and 11 more
- 2YGF · L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 11 more
- 3C11 · Yeast Hsp82 N-terminal domain-Geldanamycin complex: effects of mutants 98-99 KS-AA · GDM A300 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 4XDM · N-terminal domain of Hsp90 from Dictyostelium discoideum in complex with Geldanamycin · GDM A301 · binds ASN40, ALA41, ASP43, ALA44, LYS47, ASP82, ILE85, MET87 and 10 more
- 1A4H · Structure of the N-terminal domain of the yeast HSP90 chaperone in complex with… · GDM A300 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 1YET · Geldanamycin bound to the HSP90 geldanamycin-binding domain · GDM A275 · binds ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96, MET98 and 11 more
- 2ESA · GRP94 N-terminal domain bound to geldanamycin: effects of mutants 168- 169 ks-aa · GDM A401 · binds ASN107, ALA108, ASP110, ALA111, LYS114, ASP149, VAL152, MET154 and 10 more
- 2EXL · GRP94 N-terminal domain bound to geldanamycin · GDM A301 · binds ASN107, ALA108, ASP110, ALA111, LYS114, ASP149, VAL152, MET154 and 10 more
- 2WEQ · Yeast HSP90 N-terminal domain li-IV mutant with geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 2YGA · E88G-N92L mutant of N-term HSP90 complexed with geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 11 more
- 2YGE · E88G-N92L mutant of N-term HSP90 complexed with geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, ARG44, ASP79, ILE82, MET84 and 11 more
- 2YGF · L89V, L93I and V136M mutant of N-term HSP90 complexed with geldanamycin · GDM A1215 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 11 more
- 3C11 · Yeast HSP82 N-terminal domain-geldanamycin complex: effects of mutants 98-99 ks-aa · GDM A300 · binds ASN37, ALA38, ASP40, ALA41, LYS44, ASP79, ILE82, MET84 and 12 more
- 4XDM · N-terminal domain of HSP90 from dictyostelium discoideum in complex with geldanamycin · GDM A301 · binds ASN40, ALA41, ASP43, ALA44, LYS47, ASP82, ILE85, MET87 and 10 more
Residues it binds most
ASP 22, ALA 22, ASN 22, GLY 22, VAL 22, LEU 20, LYS 20, ILE 20, MET 22, PHE 22 (residue and the binding sites it lines).
Found with
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