Ligand · G98
G98 · 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol
G98, 4-[2-(4-amino-2,5-dihydro-1,2,5-oxadiazol-3-yl)-6-{[(1S)-3-amino-1-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol (C24 H29 N7 O3, 463.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records…
- Component
- G98
- Formula
- C24 H29 N7 O3
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
G98 in 4 structures; the first of them:
- 3E8D · Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors · G98 A1 · binds LEU158, GLY159, LYS160, GLY161, GLY164, LYS165, VAL166, ALA179 and 20 more
- 3E8E · Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors · G98 A351 · binds LEU49, GLY50, THR51, GLY52, PHE54, GLY55, ARG56, VAL57 and 18 more
- 3E8D · Crystal structures of the kinase domain of AKT2 in complex with ATP- competitive… · G98 A1 · binds LEU158, GLY159, LYS160, GLY161, GLY164, LYS165, VAL166, ALA179 and 20 more
- 3E8E · Crystal structures of the kinase domain of PKA in complex with ATP- competitive inhibitors · G98 A351 · binds LEU49, GLY50, THR51, GLY52, PHE54, GLY55, ARG56, VAL57 and 18 more
Residues it binds most
GLY 16, GLU 16, PHE 16, LEU 16, VAL 16, MET 16, THR 16, LYS 16, ALA 16, ASP 16 (residue and the binding sites it lines).
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