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Ligand · G8M

G8M · (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclobutanecarboxylic acid

G8M, (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclobutanecarboxylic acid (C7 H11 N O4, 173.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
G8M
Formula
C7 H11 N O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

G8M in 4 structures; the first of them:

  • 4G8M · Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist… · G8M A301 · binds GLU10, TYR58, PRO86, LEU87, THR88, ARG93, LEU135, SER137 and 7 more
  • 4G8N · Crystal structure of the kainate receptor GluK3 ligand-binding domain in complex with the… · G8M A301 · binds TYR63, PRO90, LEU91, THR92, ARG97, VAL139, GLY142, ALA143 and 5 more
  • 4G8M · Crystal structure of the GLUA2 ligand-binding domain (S1S2J) in complex with the agonist… · G8M A301 · binds GLU10, TYR58, PRO86, LEU87, THR88, ARG93, LEU135, SER137 and 7 more
  • 4G8N · Crystal structure of the kainate receptor GLUK3 ligand-binding domain in complex with the… · G8M A301 · binds TYR63, PRO90, LEU91, THR92, ARG97, VAL139, GLY142, ALA143 and 5 more

Residues it binds most

THR 6, TYR 6, GLU 6, LEU 6, SER 4, ARG 6, GLY 6, MET 6, PRO 6, ALA 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • K · Potassium ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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