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Ligand · G2V

G2V · 6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-1-methylindoline

G2V, 6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-1-methylindoline (C15 H17 N3, 239.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
G2V
Formula
C15 H17 N3
Class
ligand
Structures
2
PDB entries
1

Binding sites

G2V in 2 structures; the first of them:

  • 6DAI · Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site… · G2V A503 · binds ALA47, SER49, ALA65, SER91, ASP92, PHE133, CYS134, SER175 and 8 more
  • 6DAI · Discovery of potent 2-aryl-6,7-dihydro-5HPYRROLO[ 1,2-A]IMIDAZOLES as WDR5 win-site… · G2V A503 · binds SER49, SER91, ASP92, PHE133, CYS134, SER175, PHE219, TYR260 and 3 more

Residues it binds most

PHE 4, SER 4, TYR 4, CYS 3, ASP 4, ALA 1, ILE 2, PRO 2, VAL 2, LEU 1 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide

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