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Ligand · FZL

FZL · 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

FZL, 4-(cyclohexylamino)-2-[[2-methoxy-4-(2-oxidanylidenepyrrolidin-1-yl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (C24 H27 N7 O2, 445.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
FZL
Formula
C24 H27 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FZL in 2 structures; the first of them:

  • 7CHN · Crystal structure of TTK kinase domain in complex with compound 9 · FZL A801 · binds LYS529, ILE531, GLY532, VAL539, GLN541, ALA551, LYS553, ILE586 and 14 more
  • 7CHN · Crystal structure of ttk kinase domain in complex with compound 9 · FZL A801 · binds LYS529, ILE531, VAL539, GLN541, ALA551, LYS553, MET602, GLU603 and 10 more

Residues it binds most

ILE 2, GLN 2, LYS 2, ALA 2, GLY 2, MET 2, ASN 2, ASP 2, CYS 2, GLU 2 (residue and the binding sites it lines).

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