FZI · (1S,2S)-2-{[N-({[1-(tert-butoxycarbonyl)azetidin-3-yl]methoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3R)-2-oxo-2,3-dihydro-1H-pyrrol-3-yl]propane-1-sulfonic acid

Binding sites

FZI in 2 structures; the first of them:

• 7T41 · Structure of MERS 3CL protease in complex with inhibitor 14C · FZI A402 · binds HIS41, LEU49, TYR54, PHE143, LEU144, CYS145, GLY146, SER147 and 12 more
• 7T4B · Structure of SARS-cov-2 3CL protease in complex with inhibitor 14C · FZI A402 · binds HIS41, PHE140, LEU141, ASN142, GLY143, SER144, CYS145, HIS163 and 9 more

Residues it binds most

HIS 3, CYS 3, GLN 3, LEU 3, MET 3, ASP 3, GLU 3, GLY 3, PHE 3, SER 3 (residue and the binding sites it lines).

Found with

• FWI · (1R,2S)-2-{[N-({[1-(tert-butoxycarbonyl)azetidin-3-yl]methoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3R)-2-oxo-2,3-dihydro-1H-pyrrol-3-yl]propane-1-sulfonic acid
• PG4 · Tetraethylene glycol