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Ligand · FZ8

FZ8 · 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

FZ8, 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine (C17 H17 N7, 319.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
FZ8
Formula
C17 H17 N7
Class
ligand
Structures
2
PDB entries
1

Binding sites

FZ8 in 2 structures; the first of them:

  • 3WF5 · Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative… · FZ8 A402 · binds LEU97, GLY98, LYS99, GLY100, GLY103, VAL105, ALA121, LYS123 and 9 more
  • 3WF5 · Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative… · FZ8 A402 · binds LEU97, GLY98, LYS99, GLY100, GLY103, VAL105, ALA121, LYS123 and 9 more

Residues it binds most

GLY 2, LEU 2, LYS 2, VAL 2, ALA 2, CYS 2, GLU 2, MET 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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