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Ligand · FZ1

FZ1 · 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline

FZ1, 4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-(pyridin-2-yl)quinazoline (C24 H23 N5 O, 397.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
FZ1
Formula
C24 H23 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

FZ1 in 2 structures; the first of them:

  • 4IU6 · Human Methionine Aminopeptidase in complex with FZ1: Pyridinylquinazolines Selectively… · FZ1 A405 · binds GLN129, LYS132, PRO192, TYR195, TYR196, PHE198, CYS203, HIS212 and 4 more
  • 4IU6 · Human methionine aminopeptidase in complex with FZ1: pyridinylquinazolines selectively… · FZ1 A405 · binds GLN129, LYS132, PRO192, TYR195, TYR196, PHE198, CYS203, HIS212 and 4 more

Residues it binds most

HIS 2, CYS 2, TYR 2, GLN 2, LYS 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

Found with

  • CO · Cobalt (II) ion
  • K · Potassium ion
  • SO4 · Sulfate ion

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