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Ligand · FY8

FY8 · N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide

FY8, N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide (C12 H15 Cl N2 O2, 254.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
FY8
Formula
C12 H15 Cl N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FY8 in 2 structures; the first of them:

  • 5AOM · Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan883 · FY8 A1291 · binds LEU145, TRP146, VAL147, ASP148, SER149, THR150, PRO151, CYS220 and 6 more
  • 5AOM · Structure of the P53 cancer mutant Y220C with bound small molecule PHIKAN883 · FY8 A1291 · binds LEU145, TRP146, VAL147, ASP148, SER149, THR150, PRO151, CYS220 and 6 more

Residues it binds most

PRO 8, THR 8, CYS 8, ASP 4, GLU 8, GLY 4, LEU 4, SER 4, TRP 4, VAL 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol

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