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Ligand · FRX

FRX · (S)-2-chloro-N-(1-(2-(2-hydroxyethylamino)-2-oxoethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-6H-thieno[2,3-b]pyrrole-5-carboxamide

FRX, (S)-2-chloro-N-(1-(2-(2-hydroxyethylamino)-2-oxoethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-6H-thieno[2,3-b]pyrrole-5-carboxamide (C20 H19 Cl N4 O4 S, 446.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
FRX
Formula
C20 H19 Cl N4 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

FRX in 2 structures; the first of them:

  • 2IEI · Crystal structure of rabbit muscle glycogen phosphorylase in complex with… · FRX A904 · binds ARG60, LEU63, VAL64, TRP67, PRO188, TRP189, GLU190, LYS191 and 15 more
  • 2IEI · Crystal structure of rabbit muscle glycogen phosphorylase in complex with… · FRX A904 · binds ARG60, LEU63, VAL64, TRP67, PRO188, TRP189, GLU190, LYS191 and 15 more

Residues it binds most

PRO 4, ARG 4, LEU 4, PHE 4, TRP 4, VAL 4, ASN 4, GLU 4, GLY 4, HIS 4 (residue and the binding sites it lines).

Found with

  • PLR · (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl dihydrogen phosphate

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