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Ligand · FRV

FRV · 4-{[4-(1-cyclopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide

FRV, 4-{[4-(1-cyclopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide (C18 H20 N6 O2 S, 384.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
FRV
Formula
C18 H20 N6 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

FRV in 2 structures; the first of them:

  • 2W06 · Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5c · FRV A1300 · binds ILE10, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more
  • 2W06 · Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5C · FRV A1300 · binds ILE10, GLY13, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more

Residues it binds most

ALA 2, ASP 2, GLN 2, LEU 2, LYS 2, PHE 2, VAL 2, GLU 2, GLY 2, HIS 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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