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Ligand · FRT

FRT · N-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide

FRT, N-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide (C20 H26 N6 O3 S, 430.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
FRT
Formula
C20 H26 N6 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

FRT in 2 structures; the first of them:

  • 2W05 · Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5b · FRT A1299 · binds ILE10, GLY11, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more
  • 2W05 · Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5B · FRT A1299 · binds ILE10, GLY11, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more

Residues it binds most

ASP 2, GLN 2, LEU 2, LYS 2, PHE 2, VAL 2, ALA 2, ASN 2, GLU 2, GLY 2 (residue and the binding sites it lines).

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