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Ligand · FRI

FRI · 2-guanidino-4-methyl-pentanoic acid [2-(4-{5-[4-(4-acetylamino-benzyloxy)-2,3-dichloro-phenyl]-2-methyl-2H-pyrazol-3-yl}-piperidin-1-yl)-2-oxo-ethyl]-amide

FRI, 2-guanidino-4-methyl-pentanoic acid [2-(4-{5-[4-(4-acetylamino-benzyloxy)-2,3-dichloro-phenyl]-2-methyl-2H-pyrazol-3-yl}-piperidin-1-yl)-2-oxo-ethyl]-amide (C33 H42 Cl2 N8 O4, 685.6 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
FRI
Formula
C33 H42 Cl2 N8 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

FRI in 2 structures; the first of them:

  • 1QVN · Structure of SP4160 Bound to IL-2 V69A · FRI A201 · binds PRO34, LYS35, ARG38, MET39, THR41, PHE42, LYS43, PHE44 and 13 more
  • 1QVN · Structure of SP4160 bound to il-2 V69A · FRI A201 · binds PRO34, LYS35, ARG38, MET39, THR41, PHE42, LYS43, PHE44 and 13 more

Residues it binds most

LYS 8, ALA 8, PHE 8, THR 8, GLU 8, LEU 8, PRO 8, ARG 8, MET 8, TYR 8 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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