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Ligand · FQW

FQW · 2-amino-5-phenethyl-6-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

FQW, 2-amino-5-phenethyl-6-phenyl-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (C20 H18 N4 O, 330.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
FQW
Formula
C20 H18 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

FQW in 2 structures; the first of them:

  • 4CMK · Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary… · FQW A1270 · binds ARG14, SER95, PHE97, ASP161, MET163, CYS168, PHE171, TYR174 and 7 more
  • 4CMK · Crystal structure of pteridine reductase 1 (PTR1) from trypanosoma brucei in ternary… · FQW A1270 · binds ARG14, SER95, PHE97, ASP161, MET163, CYS168, PHE171, TYR174 and 7 more

Residues it binds most

MET 8, PHE 8, ARG 8, ASP 8, CYS 8, GLY 8, LEU 6, PRO 8, SER 8, TRP 8 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • ACT · Acetate ion

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