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Ligand · FP4

FP4 · 3-(4-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}-1H-indazol-3-yl)propan-1-ol

FP4, 3-(4-{[2-(pyrimidin-2-yl)furo[2,3-c]pyridin-3-yl]amino}-1H-indazol-3-yl)propan-1-ol (C21 H18 N6 O2, 386.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
FP4
Formula
C21 H18 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

FP4 in 2 structures; the first of them:

  • 3PRI · Crystal Structure of Human B-Raf Kinase in Complex with a Non-Oxime Furopyridine Inhibitor · FP4 A727 · binds ILE463, GLY464, SER465, GLY466, VAL471, ALA481, LYS483, GLU501 and 11 more
  • 3PRI · Crystal structure of human B-RAF kinase in complex with a non-oxime furopyridine inhibitor · FP4 A727 · binds ILE463, GLY464, SER465, GLY466, VAL471, ALA481, LYS483, GLU501 and 11 more

Residues it binds most

GLY 4, ILE 4, ASN 4, SER 4, ALA 4, ASP 4, CYS 4, GLN 4, GLU 4, LEU 4 (residue and the binding sites it lines).

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