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Ligand · FOJ

FOJ · 3-{[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-2,3-dihydro-1H-1-benzothiophen-5-yl]oxy}-5-fluorobenzonitrile

FOJ, 3-{[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-2,3-dihydro-1H-1-benzothiophen-5-yl]oxy}-5-fluorobenzonitrile (C16 H8 F5 N O4 S, 405.3 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every…

Component
FOJ
Formula
C16 H8 F5 N O4 S
Class
ligand
Structures
1
PDB entries
1

Binding sites

FOJ in 1 structure; the first of them:

  • 6D09 · Crystal structure of PT2440 bound to HIF2A-B*:ARNT-B* complex · FOJ A401 · binds PHE244, SER246, HIS248, MET252, PHE254, ALA277, PHE280, TYR281 and 13 more

Residues it binds most

MET 1, PHE 1, SER 1, HIS 1, TYR 1, ALA 1, ASN 1, CYS 1, GLY 1, ILE 1 (residue and the binding sites it lines).

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