Ligand · FML

FML · 6-(2,4-difluorophenoxy)-N-[(1S)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine

FML, 6-(2,4-difluorophenoxy)-N-[(1S)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine (C15 H15 F2 N5 O3 S, 383.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component: FML
Formula: C15 H15 F2 N5 O3 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

FML in 2 structures; the first of them:

3FML · P38 kinase crystal structure in complex with RO6224 · FML A361 · binds VAL30, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84, LEU86 and 11 more
3FML · P38 kinase crystal structure in complex with RO6224 · FML A361 · binds VAL30, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84, LEU86 and 11 more

Residues it binds most

LEU 2, VAL 2, ALA 2, ASP 2, GLY 2, HIS 2, ILE 2, LYS 2, MET 2, THR 2 (residue and the binding sites it lines).

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