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Ligand · FMF

FMF · 2-deoxy-2-fluoro-beta-D-mannopyranosyl fluoride

FMF, 2-deoxy-2-fluoro-beta-D-mannopyranosyl fluoride (C6 H10 F2 O4, 184.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
FMF
Formula
C6 H10 F2 O4
Class
sugar
Structures
2
PDB entries
1

Binding sites

FMF in 2 structures; the first of them:

  • 1QX1 · Golgi alpha-mannosidase II D341N mutant complex with 2-F-mannosyl-F · FMF A2003 · binds HIS90, ASP92, TRP95, ASP204, PHE206, ARG228, TYR269, ASN341 and 6 more
  • 1QX1 · Golgi alpha-mannosidase II D341N mutant complex with 2-F-mannosyl-F · FMF A2003 · binds HIS90, ASP92, TRP95, ASP204, PHE206, ARG228, TYR269, ASN341 and 6 more

Residues it binds most

ASP 2, ARG 2, HIS 2, TRP 2, TYR 2, ASN 2, PHE 2, THR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • MPD · (4S)-2-methyl-2,4-pentanediol

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