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Ligand · FMB

FMB · Formycin B

FMB, Formycin B (C10 H12 N4 O5, 268.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
FMB
Formula
C10 H12 N4 O5
Class
ligand
Structures
4
PDB entries
4

Binding sites

FMB in 4 structures; the first of them:

  • 1A69 · Purine nucleoside phosphorylase in complex with formycin B and sulphate (phosphate) · FMB A240 · binds MET64, ARG87, SER90, CYS91, GLY92, PHE159, VAL178, GLU179 and 9 more
  • 1JDZ · Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase with formycin B and… · FMB A270 · binds ILE64, ARG86, THR89, THR90, GLY91, PHE160, VAL179, GLU180 and 5 more
  • 1PR1 · Escherichia coli Purine Nucleoside Phosphorylase Complexed with Formycin B and… · FMB A245 · binds MET64, GLY65, ARG87, SER90, CYS91, GLY92, PHE159, VAL178 and 5 more
  • 1TC1 · A 1.4 ångström crystal structure for the hypoxanthine phosphoribosyltransferase of… · FMB A900 · binds ILE113, ASP115, LYS143, ALA163, PHE164, VAL165, LEU170, ASP171

Residues it binds most

GLU 9, MET 9, ARG 9, GLY 9, SER 9, ASP 11, PHE 11, VAL 11, ILE 8, CYS 6 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • PO4 · Phosphate ion
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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