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Ligand · FM2

FM2 · 2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

FM2, 2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (C11 H16 N5 O4 +1, 282.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
FM2
Formula
C11 H16 N5 O4 +1
Class
ligand
Structures
2
PDB entries
1

Binding sites

FM2 in 2 structures; the first of them:

  • 1K9S · Purine nucleoside phosphorylase from E. COLI in complex with formycin a derivative and… · FM2 A9901 · binds MET64, ARG87, SER90, CYS91, GLY92, PHE159, VAL178, GLU179 and 8 more
  • 1K9S · Purine nucleoside phosphorylase from E. COLI in complex with formycin a derivative and… · FM2 A9901 · binds MET64, ARG87, SER90, CYS91, GLY92, PHE159, VAL178, GLU179 and 8 more

Residues it binds most

ARG 6, GLU 6, MET 6, SER 6, ILE 6, ASP 6, CYS 6, GLY 6, HIS 6, PHE 6 (residue and the binding sites it lines).

Found with

  • FM1 · 2-hydroxymethyl-5-(7-methylamino-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-tetrahydro-furan-3,4-diol
  • PO4 · Phosphate ion

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