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Ligand · FM0

FM0 · (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid

FM0, (3R)-3-(fluoromethyl)-3-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}pentanoic acid (C6 H13 F O10 P2, 326.1 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues…

Component
FM0
Formula
C6 H13 F O10 P2
Class
ligand
Structures
8
PDB entries
4

Binding sites

FM0 in 8 structures; the first of them:

  • 3QT7 · Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase… · FM0 A328 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER33, SER107 and 10 more
  • 3QT8 · Crystal structure of mutant S192A Staphylococcus epidermidis mevalonate diphosphate… · FM0 A328 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER107, SER139 and 9 more
  • 4DPT · Crystal structure of Staphylococcus epidermidis mevalonate diphosphate decarboxylase… · FM0 B401 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER33, SER107 and 10 more
  • 4DPU · Crystal structure of Staphylococcus epidermidis S192A mevalonate diphosphate… · FM0 A401 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER107, GLY138 and 10 more
  • 3QT7 · Crystal structure of staphylococcus epidermidis mevalonate diphosphate decarboxylase… · FM0 A328 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER33, SER107 and 10 more
  • 3QT8 · Crystal structure of mutant S192A staphylococcus epidermidis mevalonate diphosphate… · FM0 A328 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER107, SER139 and 9 more
  • 4DPT · Crystal structure of staphylococcus epidermidis mevalonate diphosphate decarboxylase… · FM0 B401 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER33, SER107 and 10 more
  • 4DPU · Crystal structure of staphylococcus epidermidis S192A mevalonate diphosphate… · FM0 A401 · binds ALA14, LYS17, TYR18, TRP19, LYS21, ILE27, SER107, GLY138 and 10 more

Residues it binds most

SER 14, ALA 14, ARG 14, LYS 14, MET 14, GLY 14, ASP 14, ILE 14, TRP 14, TYR 14 (residue and the binding sites it lines).

Found with

  • AGS · Phosphothiophosphoric acid-adenylate ester
  • GOL · Glycerol

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