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Ligand · FLZ

FLZ · 8-methyl-6-phenoxy-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

FLZ, 8-methyl-6-phenoxy-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (C19 H20 N4 O3, 352.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
FLZ
Formula
C19 H20 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

FLZ in 2 structures; the first of them:

  • 3FLZ · P38 kinase crystal structure in complex WITH 8-Methyl-6-phenoxy-2-(tetrahydro-pyran-4-ylam… · FLZ A361 · binds GLY33, ALA34, VAL38, ALA51, LYS53, LEU75, ILE84, LEU104 and 11 more
  • 3FLZ · P38 kinase crystal structure in complex with 8-methyl-6-phenoxy-2… · FLZ A361 · binds GLY33, ALA34, VAL38, ALA51, LYS53, LEU75, ILE84, LEU104 and 11 more

Residues it binds most

LEU 2, ALA 2, ASP 2, GLY 2, VAL 2, ASN 2, HIS 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

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