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Ligand · FLI

FLI · (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,28R)-3-hexyl-4,6,8,10,12,14,16-heptahydroxy-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one

FLI, (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,28R)-3-hexyl-4,6,8,10,12,14,16-heptahydroxy-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one (C35 H58 O9, 622.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
FLI
Formula
C35 H58 O9
Class
ligand
Structures
2
PDB entries
1

Binding sites

FLI in 2 structures; the first of them:

  • 3ABA · Crystal structure of CYP105P1 in complex with filipin I · FLI A404 · binds THR79, GLN80, LYS81, PRO82, LEU88, TRP89, MET172, MET173 and 19 more
  • 3ABA · Crystal structure of CYP105P1 in complex with filipin I · FLI A404 · binds THR79, GLN80, LYS81, PRO82, LEU88, TRP89, MET172, MET173 and 19 more

Residues it binds most

GLY 2, THR 2, LEU 2, MET 2, VAL 2, ALA 2, ASN 2, GLN 2, GLU 2, ILE 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • SO4 · Sulfate ion

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