FKY · 2-{[(3R,4S)-3-fluoro-1-{[4-(trifluoromethoxy) phenyl]acetyl}piperidin-4-yl]oxy}-5-(1-methyl-1H-imidazol-4-yl)pyridine-3-carboxamide

Binding sites

FKY in 4 structures; the first of them:

• 6CZ4 · Structure of the PTK6 kinase domain bound to a type II inhibitor… · FKY A9001 · binds LEU197, GLY198, VAL205, ALA217, MET239, LEU242, ILE247, LEU248 and 16 more
• 6DKB · Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10b. · FKY A4000 · binds LEU516, VAL524, ALA542, LEU564, LEU567, ILE572, VAL573, PHE589 and 14 more
• 6CZ4 · Structure of the PTK6 kinase domain bound to a type II inhibitor 2… · FKY A9001 · binds LEU197, VAL205, ALA217, MET239, LEU242, ILE247, LEU248, THR264 and 15 more
• 6DKB · Crystal structure of trk-a in complex with the pan-trk kinase inhibitor, compound 10B. · FKY A4000 · binds LEU516, VAL524, ALA542, LEU564, LEU567, VAL573, PHE589, GLU590 and 12 more

Residues it binds most

LEU 4, GLY 4, PHE 4, VAL 4, ALA 4, MET 4, ILE 4, ASP 4, GLU 4, HIS 4 (residue and the binding sites it lines).