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Ligand · FKT

FKT · 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3, 6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide

FKT, 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3, 6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide (C35 H33 F3 N8 O3, 670.7 g/mol), in the…

Component
FKT
Formula
C35 H33 F3 N8 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

FKT in 2 structures; the first of them:

  • 7XAF · The crystal structure of TrkA kinase in complex with… · FKT A801 · binds LEU516, GLY517, GLU518, GLY519, GLY522, LYS523, VAL524, ALA542 and 22 more
  • 7XAF · The crystal structure of trka kinase in complex with 4^6,14-dimethyl… · FKT A801 · binds LEU516, GLY517, GLU518, GLY519, GLY522, LYS523, VAL524, ALA542 and 22 more

Residues it binds most

LEU 2, GLY 2, GLU 2, ILE 2, PHE 2, LYS 2, MET 2, VAL 2, ALA 2, ASP 2 (residue and the binding sites it lines).

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