Ligand · FKN

FKN · 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidine

FKN, 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidine (C18 H11 Cl F2 N4 O3 S, 436.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component: FKN
Formula: C18 H11 Cl F2 N4 O3 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

FKN in 2 structures; the first of them:

3FKN · P38 kinase crystal structure in complex with RO7125 · FKN A361 · binds VAL30, TYR35, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84 and 12 more
3FKN · P38 kinase crystal structure in complex with RO7125 · FKN A361 · binds VAL30, TYR35, VAL38, ALA51, VAL52, LYS53, LEU75, ILE84 and 12 more

Residues it binds most

LEU 2, VAL 2, ALA 2, ASP 2, GLY 2, HIS 2, ILE 2, LYS 2, MET 2, THR 2 (residue and the binding sites it lines).

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