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Ligand · FJF

FJF · 5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione

FJF, 5-[(2~{S},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-1~{H}-pyrimidine-2,4-dione (C9 H12 N2 O6, 244.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with…

Component
FJF
Formula
C9 H12 N2 O6
Class
ligand
Structures
5
PDB entries
4

Binding sites

FJF in 5 structures; the first of them:

  • 7VTG · Pseudouridine bound structure of Pseudouridine kinase (PUKI) S30A mutant from Escherichia… · FJF A401 · binds SER12, ASN14, ASP16, GLY40, GLY41, VAL42, ASN45, TYR97 and 8 more
  • 7C1Y · Pseudouridine and ADP bound structure of pseudouridine kinase (puki) from arabidopsis… · FJF A402 · binds ILE10, ASP12, GLY36, GLY37, VAL38, ASN41, VAL90, ALA105 and 8 more
  • 7VSK · Crystal structure of E.COLI pseudouridine kinase psuk complexed with pseudouridine. · FJF A401 · binds SER12, ASN14, ASP16, GLY40, GLY41, VAL42, ASN45, TYR97 and 6 more
  • 7VTG · Pseudouridine bound structure of pseudouridine kinase (puki) S30A mutant from escherichia… · FJF A401 · binds SER12, ASN14, ASP16, GLY40, GLY41, VAL42, ASN45, TYR97 and 8 more
  • 7VVA · Pseudouridine bound structure of pseudouridine kinase (puki) from escherichia COLI strain… · FJF A401 · binds ASN14, ASP16, GLY40, GLY41, VAL42, ASN45, TYR97, ASN112 and 9 more

Residues it binds most

ASN 15, GLY 15, VAL 15, ASP 15, THR 13, LYS 15, SER 13, MET 13, TYR 13, ILE 2 (residue and the binding sites it lines).

Found with

  • ADP · Adenosine-5'-diphosphate
  • NA · Sodium ion

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