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Ligand · FJ4

FJ4 · 1-(5-chloro-2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone

FJ4, 1-(5-chloro-2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone (C15 H13 Cl O4, 292.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
FJ4
Formula
C15 H13 Cl O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

FJ4 in 2 structures; the first of them:

  • 4LWG · Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ4 · FJ4 A301 · binds LEU48, ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96 and 7 more
  • 4LWG · Crystal structure of the human HSP90-alpha N-domain bound to the HSP90 inhibitor FJ4 · FJ4 A301 · binds LEU48, ASN51, SER52, ASP54, ALA55, LYS58, ASP93, ILE96 and 7 more

Residues it binds most

ASP 2, GLY 2, LEU 2, ALA 2, ASN 2, ILE 2, LYS 2, MET 2, PHE 2, SER 2 (residue and the binding sites it lines).

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