FIW · (1R,2S)-1-hydroxy-2-{[N-({[2-(2-methylpropanoyl)-2-azaspiro[3.3]heptan-6-yl]oxy}carbonyl)-L-leucyl]amino}-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid

Binding sites

FIW in 2 structures; the first of them:

• 7T42 · Structure of SARS-CoV-2 3CL protease in complex with inhibitor 2c · FIW A502 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 9 more
• 7T42 · Structure of SARS-cov-2 3CL protease in complex with inhibitor 2C · FIW A502 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, SER144, CYS145 and 9 more

Residues it binds most

HIS 4, MET 4, LEU 4, ARG 4, ASN 4, ASP 4, CYS 4, GLN 4, GLU 4, PHE 4 (residue and the binding sites it lines).

Found with

• FIK · (1S,2S)-2-[(N-{[(2-acetyl-2-azaspiro[3.3]heptan-6-yl) oxy]carbonyl}-L-leucyl)amino]-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid
• PG4 · Tetraethylene glycol